Andrea J Romanowski

she/her/hers



Contact

Andrea J Romanowski

PhD Candidate


Curriculum vitae



Department of Pharmacology

University of Maryland School of Medicine




Andrea J Romanowski

she/her/hers



Department of Pharmacology

University of Maryland School of Medicine



I am a developmental neuroscientist completing my doctorate training at the University of Maryland School of Medicine. As a PhD candidate in the Poulopoulos Lab, I investigate how genetics inform brain circuit wiring, and how mutations in neuropsychiatric risk-genes can alter the way circuits form. 
I am currently looking for a postdoctoral position where I can utilize my CRISPR expertise to continue to investigate cortical miswiring in neuropsychiatric diseases in non-human primate models like marmosets. 

As an early career scientist and future independent investigator, my goal is to encourage, inspire, and support trainees to pursue careers in neuroscience and build a sense of belonging within the scientific community. 

Projects


Circuit development


What instructs the assembly of circuit formation during early development? How do genetics inform on circuit development, and can we link genetic mutations with wiring pathologies?


CRISPR editing in the developing brain


How can we use CRISPR technology to investigate brain wiring? How can current CRISPR technology be modified to be more precise, more efficient, and even perform new functions?


Neuropsychiatric risk-gene dosage


How do changes in gene dosage affect circuit wiring that can lead to neuropsychiatric disorders? How can we better model polygenic diseases like schizophrenia?

Publications


Neuronal mTOR outposts: implications for translation, signaling, and plasticity


B Altas, AJ Romanowski, GW Bunce, A Poulopoulos

Frontiers in Cellular Neuroscience, vol. 16, 2022


Phosphorylation Determines Whether Neuroligin-3 is at Excitatory or Inhibitory Synapses in Different Regions of the Brain


B Altas, LP Tuffy, A Patrizi, K Dimova, T Soykan, AJ Romanowski, CD Robertson, SN Khim, GW Bunce, MC Ambrozkiewicz, O Yagensky, D Krueger-Burg, M Hammer, H Hsiao, PR Laskowski, L Dyck, M Sassoe-Pognetto, JJE Chua, H Urlaub, O Jahn, N Brose, A Poulopoulos

BioRxiv, 2022


NPRL3 loss alters neuronal morphology, mTOR localization, cortical lamination, and seizure threshold


PH Iffland, ME Everett, KM Cobb-Pitstick, LE Bowser, AE Barnes, JK Babus, AJ Romanowski, M Baybis, S Elziny, EG Puffenberger, C Gonzaga-Jauregui, A Poulopoulos, VJ Carson, PB Crino

Brain, 2022


Cas9 fusions for precision in vivo editing


RR Richardson, M Steyert, SN Khim, AJ Romanowski, J Inen, B Altas, A Poulopoulos

Biorxiv, 2020

Share



Follow this website


You need to create an Owlstown account to follow this website.


Sign up

Already an Owlstown member?

Log in